Basic Information
VIS ID
TVIS44028918
Fusion event
HTLV-1-ZNF800 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
q31.33
Reference genome
NCBI36/hg18
Start
126792649/127365359 (Hg38)
End
126792649/127365359 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZNF800
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-128-3p ; hsa-mir-101-3p ; hsa-mir-27a-3p ; hsa-mir-106b-5p ; hsa-mir-20a-5p ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-4473 ; hsa-mir-513a-5p ; hsa-mir-4671-3p ; hsa-mir-27b-3p ; hsa-mir-216a-3p ; hsa-mir-3681-3p ; hsa-mir-144-3p ; hsa-mir-454-3p ; hsa-mir-130a-3p ; hsa-mir-130b-3p ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-3666 ; hsa-mir-4295 ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-330-3p ; hsa-mir-6835-3p ; hsa-mir-3591-5p ; hsa-mir-153-5p ; hsa-mir-4680-5p ; hsa-mir-519d-5p ; hsa-mir-3145-5p ; hsa-mir-3646 ; hsa-mir-3662 ; hsa-mir-98-3p ; hsa-let-7f-1-3p ; hsa-let-7b-3p ; hsa-let-7a-3p ; hsa-mir-4326 ; hsa-mir-1284 ; hsa-mir-8067 ; hsa-mir-4666a-3p ; hsa-mir-6508-5p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-3680-5p ; hsa-mir-4803 ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-17-5p
Nearest miRNA
hsa-mir-10525/Upstream/307175; hsa-mir-10399/Downstream/716502;
Nearest TSS
ENST00000635602/Upstream/15231; ENST00000448311/Downstream/8206;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/17180, chr7-CpG: 122/Downstream/26441
Upstream sequence
AACAGAAACCATAAGTAACCAGAAATGAAGAGGAATCTCACATGTAGAGAAGCTATACAGATTAGATCATGTAATGGGAAAAGAAGTAAAACCCAAGACA
Downstream sequence
GACTGTTGACTAATGATAAGATAAGCCTGAAGATAACTGAAGTGTTGTTCCTGCCTTCCTTCTTTCTTCATcattctcttagcaactgttgtgtgctagg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate