Basic Information
VIS ID
TVIS44028925
Fusion event
HTLV-1-POU6F2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
p14.1
Reference genome
NCBI36/hg18
Start
39267258/39261134 (Hg38)
End
39267258/39261134 (Hg38)
Orient
-
Location type
Intronic
Target gene
POU6F2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-505-5p ; hsa-mir-545-3p ; hsa-mir-3120-3p ; hsa-mir-7850-5p ; hsa-mir-3978 ; hsa-mir-6124 ; hsa-mir-3148 ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa
Nearest miRNA
hsa-mir-1183/Upstream/2341702; hsa-mir-10399/Downstream/3889761;
Nearest TSS
ENST00000635602/Upstream/175273; ENST00000416452/Downstream/145212;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/284805, chr7-CpG: 58/Downstream/152782
Nearest cancer related gene
POU6F2(TSG, No orient, 0)
Upstream sequence
accacacatctacataacacatacacacatgcacacacacacacacacacacacacacCCCACGCCACAGATCTGTCTCCTGCTTCCTTTGGTCAACAAT
Downstream sequence
GAAAGCTGCCACAGAGACAAAGTTAGGCAAAGGTTCTGTGACCACTAATTCCACAACTGCCAGGGCTCAGCCAGGCCACCTCTCCTGCTCCTGCAGGAAC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate