Basic Information
VIS ID
TVIS44028926
Fusion event
HTLV-1-PDE11A integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
q31.2
Reference genome
NCBI36/hg18
Start
178602390/178029417 (Hg38)
End
178602390/178029417 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2G
Target gene
PDE11A
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-1273e ; hsa-mir-6807-5p ; hsa-mir-1233-3p ; hsa-mir-1225-3p ; hsa-mir-4786-5p ; hsa-mir-6840-3p ; hsa-mir-199b-5p ; hsa-mir-199a-5p ; hsa-mir-665 ; hsa-mir-4302 ; hsa-mir-4433a-3p ; hsa-mir-335-3p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-3157-5p ; hsa-mir-30a-3p ; hsa-mir-876-3p ; hsa-mir-323a-5p ; hsa-mir-4691-3p ; hsa-mir-3910 ; hsa-mir-7977 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-383-3p ; hsa-mir-433-5p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-1827 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p
Nearest miRNA
hsa-mir-10b/Upstream/715535; hsa-mir-1244-1/Downstream/1831419;
Nearest TSS
ENST00000437798/Upstream/102408; ENST00000493048/Downstream/43338;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/410362, chr2-CpG: 23/Downstream/43451
Upstream sequence
taggaacaataataaaaagataactagtgaaatcaaatatttaaacatttagaatacatttctgaattacccatcaatcaaaaaattaaaatagaagtta
Downstream sequence
taaaatacttagaaaatactaagaaaaataatgtctaaatataaaaataccaggatgattacacatcatatatcaaaaccgtggtccacagttaaagagt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate