Basic Information
VIS ID
TVIS44028940
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p35.1
Reference genome
NCBI36/hg18
Start
34120603/33882415 (Hg38)
End
34120603/33882415 (Hg38)
Orient
-
Location type
Intronic
Target gene
CSMD2 ; CSMD2-AS1
miRNAs that regulate target gene
hsa-mir-3941 ; hsa-mir-125b-2-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-495-5p ; hsa-mir-4650-5p ; hsa-mir-1972
Nearest miRNA
hsa-mir-12136/Upstream/549923; hsa-mir-101-1/Downstream/787184;
Nearest TSS
ENST00000473358/Upstream/6949; ENST00000373374/Downstream/282859;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/248896, chr1-CpG: 160/Downstream/280767
Upstream sequence
AGGACTGAAAGTGACTTAGGTGAAGACTGATGGTCTAATGAGACAGCTTCAAAGGACAGGCTGTCAATGGACAACATTTGTAATTTCATACTTTCTCTAA
Downstream sequence
AGCTGCCTATGTCACGACTCTTCCCACTTGAGAATGTTCAGACCAAAGAGAAATGAAACATATCTACCTTTCTATTGACTGTTAATCCTTTGTAGAATAG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate