Basic Information
VIS ID
TVIS44028978
Fusion event
HTLV-1-PTAR1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr9
Cytoband
q21.12
Reference genome
NCBI36/hg18
Start
71562261/69757525 (Hg38)
End
71562261/69757525 (Hg38)
Orient
-
Location type
Intronic
Target gene
PTAR1
miRNAs that regulate target gene
hsa-mir-210-3p ; hsa-mir-1-3p ; hsa-mir-7-5p ; hsa-mir-21-5p ; hsa-mir-15b-5p ; hsa-mir-30c-5p ; hsa-mir-15a-5p ; hsa-mir-16-2-3p ; hsa-mir-195-3p ; hsa-mir-4662a-3p ; hsa-mir-4803 ; hsa-mir-379-3p ; hsa-mir-380-3p ; hsa-mir-411-3p ; hsa-mir-4495 ; hsa-mir-374a-5p ; hsa-mir-155-5p ; hsa-mir-135b-3p ; hsa-mir-4325 ; hsa-mir-7703 ; hsa-mir-1206 ; hsa-mir-8065 ; hsa-mir-891b ; hsa-mir-6783-5p ; hsa-mir-4703-5p ; hsa-mir-3942-5p ; hsa-mir-32-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-25-3p ; hsa-mir-1827 ; hsa-mir-4704-3p ; hsa-mir-449c-5p ; hsa-mir-34b-5p ; hsa-mir-2682-5p ; hsa-mir-4752 ; hsa-mir-8056 ; hsa-mir-3691-5p ; hsa-mir-376c-5p ; hsa-mir-376b-5p ; hsa-mir-4657 ; hsa-mir-4491 ; hsa-mir-8066 ; hsa-mir-599 ; hsa-mir-3161 ; hsa-mir-1266-3p ; hsa-mir-4793-5p ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30a-5p
Nearest miRNA
hsa-mir-101-2/Upstream/28523690; hsa-let-7a-1/Downstream/1052450;
Nearest TSS
ENST00000422679/Upstream/23267; ENST00000480564/Downstream/2416;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/84360, chr9-CpG: 74/Downstream/1967
Upstream sequence
TATTGAGTGGCAACTAAGTACCACTGTGTGAGGTGATTTTCCTGTTTTCATCAGCCTCACAAGATCAAGAGGAAACTGAGGCTGAGAGAAGGTACCTATT
Downstream sequence
CACATCATACAGTAACAAAATCCACATCTCACCACTGCATCCTCAACTCCTTCTGGCTAAATATTTCTACATAAACAAAGTCAATGTATTTAATGAAGTA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate