Basic Information
VIS ID
TVIS44028980
Fusion event
HTLV-1-NCOR1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
NCBI36/hg18
Start
16059769/16215730 (Hg38)
End
16059769/16215730 (Hg38)
Orient
-
Location type
Intronic
Target gene
NCOR1
miRNAs that regulate target gene
hsa-mir-1301-3p ; hsa-mir-615-3p ; hsa-mir-484 ; hsa-mir-320a ; hsa-let-7b-5p ; hsa-mir-34a-3p
Nearest miRNA
hsa-mir-1253/Upstream/964034; hsa-mir-10226/Downstream/66284;
Nearest TSS
ENST00000595228/Upstream/170; ENST00000463810/Downstream/1461;
Nearest CpG islands
chr17-CpG: 118/Target, None/Upstream, None/Downstream
Upstream sequence
CGCTGGCCGGGCGCCTCTCCTACCTCGGCGGAGCTTCCCGGGTCGCGCTGCGCCCGGTCTCTTCATGTCTCCTCTAGGCCTGGCAGCGGCGGTCCTCTCG
Downstream sequence
GACGGATACGGGGCCGAGCAGCGCCCAGCCGGATCCAGCGCTGCTGCCATCGTGCCCTGGGCTTGTGCGCCCCCCGCCTGCCCGTCTGTTCCGCGCGCCC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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