Basic Information
VIS ID
TVIS44028984
Fusion event
HTLV-1-AUTS2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
q11.22
Reference genome
NCBI36/hg18
Start
69752734/70649812 (Hg38)
End
69752734/70649812 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7J
Target gene
AUTS2
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-222-3p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-1183/Upstream/3535415; hsa-mir-10399/Downstream/657860;
Nearest TSS
ENST00000635602/Upstream/53727; ENST00000489774/Downstream/44246;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/53342, chr7-CpG: 218/Downstream/43962
Upstream sequence
agagatgggccttcaccatgttggccaggctggtcttgaattctggacctcgtgattcacccgcctcggtgtccaaagtgctgggattataggcgtgagc
Downstream sequence
caccgcacccggccCCAGTGGTGATTTTGTAGGTCAGCAGAGATGATCTGTGTGCCACATTTCCTTGTAGCTTAACAATGGGCCTCAATCATGTGGTGCT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate