Basic Information
VIS ID
TVIS44028985
Fusion event
HTLV-1-BCORL1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chrX
Cytoband
q26.1
Reference genome
NCBI36/hg18
Start
129017341/130055685 (Hg38)
End
129017341/130055685 (Hg38)
Orient
-
Location type
Intronic
Target gene
BCORL1
miRNAs that regulate target gene
hsa-mir-192-5p ; hsa-mir-760 ; hsa-mir-196a-5p ; hsa-let-7b-5p ; hsa-mir-4290 ; hsa-mir-4285 ; hsa-mir-5008-5p ; hsa-mir-660-3p ; hsa-mir-4667-3p ; hsa-mir-1277-5p ; hsa-mir-6083 ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-3119 ; hsa-mir-892b ; hsa-mir-587 ; hsa-mir-1250-3p
Nearest miRNA
hsa-let-7f-2/Upstream/8684632; hsa-mir-105-1/Downstream/4113693;
Nearest TSS
ENST00000429181/Upstream/41218; ENST00000257017/Downstream/25747;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/70971, chrX-CpG: 87/Downstream/4347
Nearest cancer related gene
BCORL1(TSG, No orient, 0)
Upstream sequence
ATTTTGGAAGAGGTGGTCACTGATTGCGTGCTCACCATTTAGCTGAAAGCCGGGCCAGGCATTGCAGGGGACAGGAGAAGACATTTGCCTCAGCTATACC
Downstream sequence
CAAGGAGCCTGTGGTTTAGCAGGGGACGGGGGAGCCAGACTGGCAGTGAGTTATAATGGGAGACATTGATGGTCGTGCAGCCTTTGTGGGCTTTGCAGAG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate