Basic Information
VIS ID
TVIS44029010
Fusion event
HTLV-1-ECPAS integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr9
Cytoband
q31.3
Reference genome
NCBI36/hg18
Start
113180531/111378430 (Hg38)
End
113180531/111378430 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA9E
Target gene
ECPAS
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-26b-5p ; hsa-mir-16-5p ; hsa-mir-320a ; hsa-mir-185-5p ; hsa-mir-770-5p ; hsa-mir-377-3p
Nearest miRNA
hsa-let-7a-1/Upstream/107216; hsa-mir-12126/Downstream/553670;
Nearest TSS
ENST00000422679/Upstream/6642; ENST00000374374/Downstream/105249;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/339335, chr9-CpG: 230/Downstream/104334
Upstream sequence
GAAATATACAAAAAACTATGTTAAACAAATGTTAATTCATTTTTTAGATGGAAGTGTCAGTTTTCATCCAATTCACAAGACAGTGTATGAGCTGACAACC
Downstream sequence
TCTCTCCAAAAAAACAGTAAAACACTGCATGTGGTGACAGAGGGTGAGTTCTGGTAACAGTAGTGACAGTGTCATTCAAATGAACCTTGGTATCTTAACA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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