Basic Information
VIS ID
TVIS44029013
Fusion event
HTLV-1-BRAF integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
q34
Reference genome
NCBI36/hg18
Start
140256351/140910082 (Hg38)
End
140256351/140910082 (Hg38)
Orient
-
Location type
Intronic
Target gene
BRAF
miRNAs that regulate target gene
hsa-mir-744-5p ; hsa-mir-378a-5p ; hsa-mir-191-5p ; hsa-mir-143-3p ; hsa-mir-145-5p ; hsa-mir-579-3p
Nearest miRNA
hsa-mir-10399/Upstream/1865925; hsa-mir-11400/Downstream/1564445;
Nearest TSS
ENST00000635602/Upstream/73849; ENST00000563442/Downstream/14621;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/212598, chr7-CpG: 90/Downstream/14115
Nearest cancer related gene
BRAF(OG, No orient, 0)
Upstream sequence
tgcaaactgtcctgaacattgtgggatggctgacttccctgatcctttctcattaaatgctaatagtgtcctcttcctccatctttgtaacaaccaaaat
Downstream sequence
acctccGAGTATTTCATCTCATTGCATGCAATATAAAGTGCACTTTTTGTCAGCCTATCACTTTTTCCTACAATCCAGTCCCATCTAATTTTGTCAAATT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate