Basic Information
VIS ID
TVIS44029020
Fusion event
HTLV-1-LRBA integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
q31.3
Reference genome
NCBI36/hg18
Start
151790965/150650363 (Hg38)
End
151790965/150650363 (Hg38)
Orient
-
Location type
Intronic
Target gene
LRBA
miRNAs that regulate target gene
hsa-mir-1229-3p ; hsa-mir-93-3p ; hsa-mir-769-5p ; hsa-mir-615-3p
Nearest miRNA
hsa-mir-12113/Upstream/2867695; hsa-mir-1305/Downstream/1838964;
Nearest TSS
ENST00000502981/Upstream/68441; ENST00000503002/Downstream/29304;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/66430, chr4-CpG: 89/Downstream/365138
Upstream sequence
TTTATTAATATTAACATGTGGACATCTACAAAACGTAATAAGGCATTTAAAAACTGAGAAAATTTTCTACTTTTCCCAATTTCTATAAAATGTAATATGT
Downstream sequence
TATTTAATAACCAAGAAAACATTCTATTTTTTCCTAATATCTCTAAGCAGACATTAAAACTTGTTATTTGGAATGAATATTTGTTTCCAAATGAACAATG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate