Basic Information
VIS ID
TVIS44029037
Fusion event
HTLV-1-SNX11 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr17
Cytoband
q21.32
Reference genome
NCBI36/hg18
Start
43544950/48112589 (Hg38)
End
43544950/48112589 (Hg38)
Orient
+
Location type
Intronic
Target gene
SNX11
miRNAs that regulate target gene
hsa-mir-151a-5p ; hsa-mir-484 ; hsa-mir-128-3p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-1249-5p ; hsa-mir-1273a ; hsa-mir-1321 ; hsa-mir-149-3p ; hsa-mir-4270 ; hsa-mir-4419a ; hsa-mir-4433b-3p ; hsa-mir-4441 ; hsa-mir-4481 ; hsa-mir-4510 ; hsa-mir-4649-5p ; hsa-mir-4676-5p ; hsa-mir-4728-5p ; hsa-mir-4739 ; hsa-mir-4745-5p ; hsa-mir-4756-5p ; hsa-mir-4779 ; hsa-mir-575 ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-6729-5p ; hsa-mir-6754-5p ; hsa-mir-6758-5p ; hsa-mir-6785-5p ; hsa-mir-6797-5p ; hsa-mir-6847-5p ; hsa-mir-6858-3p ; hsa-mir-6883-5p ; hsa-mir-7106-5p ; hsa-mir-765 ; hsa-mir-7845-5p
Nearest miRNA
hsa-mir-10226/Upstream/75342; hsa-mir-10a/Downstream/43838;
Nearest TSS
ENST00000595228/Upstream/23; ENST00000582246/Downstream/24745;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/4777, chr17-CpG: 27/Downstream/317393
Upstream sequence
GTTGGGTGGAAAAATCTAGCGACCTGTGTTGTCAGAGCTGCCTTGCTGTGTAGCTGAAGCTGAGGGAGCTTTTCTTACCTACAGGAGGTGATTACAGTGC
Downstream sequence
GTGTTCAGGACCCCCGAGTGCAGAATGAGGGCTCCTGGAACTCTTATGTGGATTATAAGATATTCCTCCATGTGAGTACATCAAGCTTCTGTATTGGGGT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate