Basic Information
VIS ID
TVIS44029059
Fusion event
HTLV-1-ABCC1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr16
Cytoband
p13.11
Reference genome
NCBI36/hg18
Start
15972266/15970908 (Hg38)
End
15972266/15970908 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA16A
Target gene
ABCC1
miRNAs that regulate target gene
hsa-mir-345-5p ; hsa-mir-7-5p ; hsa-mir-134-5p ; hsa-mir-9-5p ; hsa-mir-1-3p ; hsa-mir-98-5p ; hsa-let-7b-5p ; hsa-mir-615-3p ; hsa-mir-339-5p ; hsa-mir-125b-5p ; hsa-mir-23b-3p ; hsa-mir-16-5p ; hsa-mir-1291 ; hsa-mir-3180-5p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-361-3p ; hsa-mir-1825 ; hsa-mir-548o-3p ; hsa-mir-1323 ; hsa-mir-5195-3p ; hsa-mir-5582-3p ; hsa-mir-145-5p ; hsa-mir-199a-5p ; hsa-mir-199b-5p ; hsa-mir-224-5p
Nearest miRNA
hsa-mir-1225/Upstream/327536; hsa-mir-11401/Downstream/329251;
Nearest TSS
ENST00000527434/Upstream/21331; ENST00000574224/Downstream/38948;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/20838, chr16-CpG: 30/Downstream/252471
Upstream sequence
ggtttcaaacccctgagctcaagccatcttcttgcctcggcctccgaaagtgttgggattacaggtgtgagccattatacctggcCTTCAACTCAGTCCC
Downstream sequence
TAAAGACAACTCCTTCTCAAGTGTTGGAAAGAACCAATGACTAATCACTTCTAGTCTGCCTTATCCCCATCTTGCTTGTGTGACTTTGGTAAGAGTTTGT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate