Basic Information
VIS ID
TVIS44029071
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
q32.1
Reference genome
NCBI36/hg18
Start
202691531/204455780 (Hg38)
End
202691531/204455780 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC110121081 ; PIK3C2B
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-128-3p ; hsa-mir-15b-5p ; hsa-mir-4469 ; hsa-mir-218-5p ; hsa-mir-4314 ; hsa-mir-4753-3p ; hsa-mir-4672 ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-30b-5p ; hsa-mir-30a-5p ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-4795-5p ; hsa-mir-4320 ; hsa-mir-548ax ; hsa-mir-548ao-5p ; hsa-mir-302d-5p ; hsa-mir-6506-5p ; hsa-mir-302b-5p ; hsa-mir-619-5p ; hsa-mir-4646-5p ; hsa-mir-3192-5p ; hsa-mir-204-3p ; hsa-mir-130b-5p ; hsa-mir-4459 ; hsa-mir-4433a-3p ; hsa-mir-6768-5p ; hsa-mir-551b-5p ; hsa-mir-101-3p ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-3973 ; hsa-mir-2114-5p ; hsa-mir-6507-3p ; hsa-mir-4774-5p ; hsa-mir-4490 ; hsa-mir-3613-3p ; hsa-mir-7151-5p ; hsa-mir-4668-3p ; hsa-mir-548c-3p ; hsa-mir-3679-3p ; hsa-mir-1236-3p ; hsa-mir-877-3p ; hsa-mir-4286 ; hsa-mir-483-3p ; hsa-mir-362-5p
Nearest miRNA
hsa-mir-101-1/Upstream/2452544; hsa-mir-1182/Downstream/992522;
Nearest TSS
ENST00000473358/Upstream/5650; ENST00000470797/Downstream/511;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/43749, chr1-CpG: 69/Downstream/38385
Upstream sequence
AGCCCAAGTCCTCCTCAGGCACTTGGCTCACCCCCGCAGCCCCATTGCACCACAATGTCACACAATGCCACACATCCTAAGACTTAGGACAGTGGTATTA
Downstream sequence
CATGCAGATAGGAAAAAGCCCTGGTGGAGGTCAAACTCAGCTTGCTCCCTAGCGGCTACTCAGCCCTGGGCTCACCTGGTAGCCCAGATGATGGGGATGC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate