Basic Information
VIS ID
TVIS44029073
Fusion event
HTLV-1-TNKS1BP1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr11
Cytoband
q12.1
Reference genome
NCBI36/hg18
Start
56841039/57316989 (Hg38)
End
56841039/57316989 (Hg38)
Orient
+
Location type
Intronic
Target gene
TNKS1BP1
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-155-5p ; hsa-mir-1-3p ; hsa-mir-93-5p ; hsa-mir-1296-5p ; hsa-mir-18a-3p ; hsa-mir-484 ; hsa-mir-125b-5p ; hsa-mir-182-5p ; hsa-mir-3157-5p ; hsa-mir-26b-5p ; hsa-mir-3151-5p ; hsa-mir-3202 ; hsa-mir-328-5p ; hsa-mir-4447 ; hsa-mir-4472 ; hsa-mir-4685-5p ; hsa-mir-4723-5p ; hsa-mir-4747-5p ; hsa-mir-491-5p ; hsa-mir-5196-5p ; hsa-mir-520d-5p ; hsa-mir-524-5p ; hsa-mir-5698 ; hsa-mir-6742-5p ; hsa-mir-6795-5p ; hsa-mir-6796-5p ; hsa-mir-6804-5p ; hsa-mir-6837-5p ; hsa-mir-6870-5p ; hsa-mir-6885-5p ; hsa-mir-6887-5p ; hsa-mir-7109-5p ; hsa-mir-7111-5p ; hsa-mir-7113-5p ; hsa-mir-7515 ; hsa-mir-9500
Nearest miRNA
hsa-mir-129-2/Upstream/573008; hsa-let-7a-2/Downstream/324209;
Nearest TSS
ENST00000527297/Upstream/5520; ENST00000534162/Downstream/5208;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/1442345, chr11-CpG: 78/Downstream/7408
Upstream sequence
agccaaagtctttctagaggccttcgagacttgacacaatccaaccccccaacccgttggtcctcactaccacctaactcctctctcactgccaggcaga
Downstream sequence
catcctggcctccttgccaggaaagcaccaatgcctttgtacttgctgtgccctctaccaagaatgctgctctccagacatgcacacagctcagcctctg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate