Basic Information
VIS ID
TVIS44029101
Fusion event
HTLV-1-ACTA2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
q23.31
Reference genome
NCBI36/hg18
Start
90695163/88945426 (Hg38)
End
90695163/88945426 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
ACTA2
miRNAs that regulate target gene
hsa-mir-484
Nearest miRNA
hsa-mir-1265/Upstream/1441472; hsa-mir-107/Downstream/117909;
Nearest TSS
ENST00000439456/Upstream/5929; ENST00000460510/Downstream/7321;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/64560, chr10-CpG: 68/Downstream/45110
Upstream sequence
AAATTTTTGTAGAAAGATAGAGCTTGGAGCATTACTGCTGATAAATTCTAACAACATTATGTATTTTTCTTTTAAGTGATAAATTGTGTGCGTAGTAGTA
Downstream sequence
GTAGTGAGCCGATAGATAAATAAAAGGCCAGATATCGTGATTCTGATATATCTTGCTGCATTTAAAATTTTTTATGTCACTTTCTCATTATTTCTTCTGT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate