Basic Information
VIS ID
TVIS44029145
Fusion event
HTLV-1-NBEA integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr13
Cytoband
q13.3
Reference genome
NCBI36/hg18
Start
34471231/34999094 (Hg38)
End
34471231/34999094 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA13A
Target gene
NBEA
miRNAs that regulate target gene
hsa-mir-548b-3p ; hsa-mir-335-5p ; hsa-mir-9-5p ; hsa-mir-128-3p ; hsa-mir-21-5p ; hsa-mir-935 ; hsa-mir-18a-5p ; hsa-mir-377-3p ; hsa-mir-485-3p ; hsa-mir-127-3p ; hsa-mir-409-5p
Nearest miRNA
hsa-mir-2276/Upstream/10836590; hsa-mir-1267/Downstream/4664940;
Nearest TSS
ENST00000623511/Upstream/56434; ENST00000497540/Downstream/70858;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/55804, chr13-CpG: 54/Downstream/471613
Upstream sequence
aagtgtccatgaaatcttcacaatttatgttcttctgccatggcttcagctggtccctccgtttggggtccctgacttccctcaacaACTAACCAAGCTT
Downstream sequence
ATATCCTTATGGTAGAAATAGAGACATACTATAAATATTTATAACAAACAAAATTGGGGTAAGAATCCTTCTTTTGTTCTATTGTTTGGTCAGTCAATAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate