Basic Information
VIS ID
TVIS44029153
Fusion event
HTLV-1-SGSM1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr22
Cytoband
q11.23
Reference genome
NCBI36/hg18
Start
23547752/24821785 (Hg38)
End
23547752/24821785 (Hg38)
Orient
+
Location type
Intronic
Target gene
SGSM1
miRNAs that regulate target gene
hsa-mir-760 ; hsa-mir-221-5p ; hsa-mir-6848-3p ; hsa-mir-3187-3p ; hsa-mir-6843-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-6131 ; hsa-mir-4755-3p ; hsa-mir-3663-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-548o-3p ; hsa-mir-1323 ; hsa-mir-4781-3p
Nearest miRNA
hsa-mir-1286/Upstream/1935406; hsa-let-7a-3/Downstream/633861;
Nearest TSS
ENST00000624155/Upstream/15466; ENST00000480523/Downstream/21675;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/15199, chr22-CpG: 147/Downstream/130399
Upstream sequence
ATCTTCCATGACTGACAGTGTGAGGAAAGGACATTGCTTTCTTATTTTCCCCCCCAAAGTCTGTATTTAAGACTTATTAAAGTCttattggagcagttat
Downstream sequence
aggttctcagaaaagctgagcagaaggtgcagagatttccctcatatcctcgaccctgccacatgtgcagcctaccccactgtcaacatcctcggccaga
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate