Basic Information
VIS ID
TVIS44029174
Fusion event
HTLV-1-EMC8 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr16
Cytoband
q24.1
Reference genome
NCBI36/hg18
Start
84381141/85790034 (Hg38)
End
84381141/85790034 (Hg38)
Orient
+
Location type
Intronic
Target gene
EMC8
miRNAs that regulate target gene
hsa-mir-484 ; hsa-mir-5000-5p ; hsa-mir-3119 ; hsa-mir-4662a-3p ; hsa-mir-632 ; hsa-mir-4288 ; hsa-mir-500a-3p ; hsa-mir-346 ; hsa-mir-6804-3p ; hsa-mir-4793-3p ; hsa-mir-3130-3p ; hsa-mir-6761-5p ; hsa-mir-877-3p ; hsa-mir-211-3p ; hsa-mir-654-3p ; hsa-mir-7845-5p ; hsa-mir-483-5p ; hsa-mir-140-3p
Nearest miRNA
hsa-mir-12128/Upstream/48334; hsa-mir-11401/Downstream/128313;
Nearest TSS
ENST00000527434/Upstream/5652; ENST00000602617/Downstream/2381;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/38509, chr16-CpG: 138/Downstream/8780
Upstream sequence
CGGCGTGCTTTGAAATGGAAGCAAGGTGGCAGACCTTTGAAGTTTTTGGGTTTCTTTTATGGTACCATGTTTCTCACCAGATGCAGCTTCCTGCAGGTCT
Downstream sequence
AAGGCCATTATTCAAAACAACAAAAGCTCATCCTGTTTTGGCATAATGGAATTTGAATACACTGTAATAAAGTCTATTCTCAGTCTGCACAAGAGGAAAC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate