Basic Information
VIS ID
TVIS44029177
Fusion event
HTLV-1-PTPN5 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr11
Cytoband
p15.1
Reference genome
NCBI36/hg18
Start
18713103/18734980 (Hg38)
End
18713103/18734980 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11C ; FRA11I
Target gene
PTPN5
Nearest miRNA
hsa-mir-210/Upstream/347120; hsa-let-7a-2/Downstream/840330;
Nearest TSS
ENST00000527297/Upstream/4236; ENST00000528646/Downstream/8862;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/13014, chr11-CpG: 123/Downstream/56045
Upstream sequence
CTCTCACAGGcagtataggggagtcattaagagtctacaccgctgagccagagaggctaggttcaaatcctgattctgacttactagcagtgtcaacatg
Downstream sequence
gacaatttactttatctccctgtgccttatctgtaatctggggatggtcattccacaatgaccttgcttatcttgtaaaggagttaactttaacaactag
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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