Basic Information
VIS ID
TVIS44029181
Fusion event
HTLV-1-TOX integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
q12.1
Reference genome
NCBI36/hg18
Start
60096846/59021733 (Hg38)
End
60096846/59021733 (Hg38)
Orient
+
Location type
Intronic
Target gene
TOX
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-223-3p
Nearest miRNA
hsa-mir-124-1/Upstream/16125458; hsa-mir-10400/Downstream/2693055;
Nearest TSS
ENST00000518652/Upstream/361889; ENST00000523683/Downstream/97307;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/361766, chr8-CpG: 175/Downstream/95842
Upstream sequence
AATACAAAAATAGATTGGTTTTCTCGAATAGTGAAATAGTTCTCTAAAACAAGGTGACTCCTGTTGTAGGCACCTCTTAAAAATTACCATAAACTGGTAT
Downstream sequence
ATACCATTTTGATTTTCCTTCAAATATATGCAGAGAATCAAAATCATGATTGAAATTCCAACCGTCACACCTGGATTCATACCATCTTTTTATTAACTTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate