Basic Information
VIS ID
TVIS44029199
Fusion event
HTLV-1-SLC39A6 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr18
Cytoband
q12.2
Reference genome
NCBI36/hg18
Start
31955758/36121797 (Hg38)
End
31955758/36121797 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA18A
Target gene
SLC39A6
miRNAs that regulate target gene
hsa-mir-32-5p ; hsa-mir-26b-5p ; hsa-mir-3163 ; hsa-mir-323a-5p ; hsa-mir-539-5p ; hsa-mir-101-3p ; hsa-mir-126-3p ; hsa-mir-548v ; hsa-mir-139-5p ; hsa-mir-135b-5p ; hsa-mir-135a-5p ; hsa-mir-889-5p ; hsa-mir-410-3p ; hsa-mir-144-3p ; hsa-mir-7849-3p ; hsa-mir-92b-3p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-1-2/Upstream/187655; hsa-mir-122/Downstream/1535338;
Nearest TSS
ENST00000575820/Upstream/54221; ENST00000541190/Downstream/318;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/54095, chr18-CpG: 126/Downstream/7159
Upstream sequence
TAGTTAATCGTAACTACTAATAAATATTGATAGTGTATCCATGTATACACGATGCTTCTGGTCTTCAAGGCCCTGCTGGTACCTTGTCTGGTCACTTATA
Downstream sequence
CAGATGTTCATCCTTGCTTTTCTTATCCTGTCATGAGTTTCAAAAGAATAGCAAAGACAGAAAACTTCAGAGCTATTAAGATATAGAAATGCTCCTCATA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate