Basic Information
VIS ID
TVIS44029202
Fusion event
HTLV-1-PLEKHG1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
q25.1
Reference genome
NCBI36/hg18
Start
151038776/150675947 (Hg38)
End
151038776/150675947 (Hg38)
Orient
+
Location type
Intronic
Target gene
PLEKHG1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-498
Nearest miRNA
hsa-mir-10398/Upstream/9992064; hsa-mir-1202/Downstream/426728;
Nearest TSS
ENST00000381078/Upstream/23922; ENST00000644913/Downstream/7665;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/74937, chr6-CpG: 133/Downstream/189813
Upstream sequence
GAAATTAAGTAGCAAAAAAGAAACTGTATAAACATTTATTGCAGATATCATTAAATACCTACAAAACATAGATGAAACGAGTAAAAAGTGAGTAAAAATA
Downstream sequence
GTTACTAATACAAGATATAATTCAAAAGAAAAAAATTCAAGATTCAGACCACAAGCCATATAATATATCACAGTGAACTCCCAATGAACTAAAGAATTAC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate