Basic Information
VIS ID
TVIS44029212
Fusion event
HTLV-1-DOCK4 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
q31.1
Reference genome
NCBI36/hg18
Start
111164031/111736739 (Hg38)
End
111164031/111736739 (Hg38)
Orient
-
Location type
Intronic
Target gene
DOCK4
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-21-5p ; hsa-mir-98-5p ; hsa-mir-1277-5p ; hsa-mir-23c ; hsa-mir-23b-3p ; hsa-mir-23a-3p ; hsa-mir-130a-5p ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-1273g-5p ; hsa-mir-203a-5p ; hsa-mir-5011-5p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-6837-3p ; hsa-mir-6754-3p ; hsa-mir-412-3p
Nearest miRNA
hsa-mir-10525/Upstream/9265208; hsa-mir-10399/Downstream/2916606;
Nearest TSS
ENST00000635602/Upstream/4225; ENST00000452714/Downstream/3475;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/8130, chr7-CpG: 106/Downstream/469066
Upstream sequence
AGGCATTGCCTGGGTGACTCACTGGATGATAACAAAAAGCCATTAAACATAGGCGTTCCTATCTTGCTCAGATTCTGCTGTTAAAATCTTATAGGAAAAC
Downstream sequence
AGCTTTTGAAGAATGATCATGAATAACTGTCTTTCATTAATCCCTTAAAGAGCATACTAGTCCTGATCATTAAAGAGCTAGAGCACTGCTTTCCACACAG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate