Basic Information
VIS ID
TVIS44029222
Fusion event
HTLV-1-ANK3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
q21.2
Reference genome
NCBI36/hg18
Start
61743867/60314103 (Hg38)
End
61743867/60314103 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10C
Target gene
ANK3
miRNAs that regulate target gene
hsa-mir-218-5p ; hsa-mir-8088 ; hsa-mir-598-5p ; hsa-mir-216b-3p ; hsa-mir-8485 ; hsa-mir-603 ; hsa-mir-503-5p ; hsa-mir-34a-5p
Nearest miRNA
hsa-mir-1265/Upstream/3009544; hsa-mir-107/Downstream/3058854;
Nearest TSS
ENST00000439456/Upstream/13621; ENST00000517854/Downstream/75627;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/407067, chr10-CpG: 60/Downstream/418924
Upstream sequence
ccctgctagagtgtgcactcttctaagacaaaaagttacctattggttactgtggtattcAGTAAATATTTTTTTGAGTGATTGAATAAATAACATTTAC
Downstream sequence
TACAGTGGTGATTCTGATTAGGATGATATTTTGAGAGAATCAAGTTAAAAAGCAAAAATTTTCAAAAGTCTTAGCTTTCATCAAGTGATGTCCAGTTACT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate