Basic Information
VIS ID
TVIS44029247
Fusion event
HTLV-1-HFM1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p22.2
Reference genome
NCBI36/hg18
Start
91625608/91387463 (Hg38)
End
91625608/91387463 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1D
Target gene
HFM1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-218-5p ; hsa-mir-2681-5p ; hsa-mir-4724-5p ; hsa-mir-4262 ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p ; hsa-mir-551b-5p
Nearest miRNA
hsa-mir-101-1/Upstream/5029776; hsa-mir-11399/Downstream/2459369;
Nearest TSS
ENST00000473358/Upstream/34826; ENST00000497611/Downstream/17272;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/365213, chr1-CpG: 62/Downstream/16856
Upstream sequence
tgtggtaacttttctgacacctcctgcttaaaacccaaaaggtcagaaggatcgtgaggccccgctttcacggtctgtattcgtactgaaaatcaagatc
Downstream sequence
aagcgagcttttgcccttctgctccacgggaggtttctgtcctccctgagctcgccttaggacacctgcgttaccgtttgacaggtgtacagccccagtc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate