Basic Information
VIS ID
TVIS44029249
Fusion event
HTLV-1-LIN7C integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr11
Cytoband
p14.1
Reference genome
NCBI36/hg18
Start
27482332/27504209 (Hg38)
End
27482332/27504209 (Hg38)
Orient
+
Location type
Intronic
Target gene
LIN7C
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-421 ; hsa-mir-155-5p ; hsa-mir-124-3p ; hsa-mir-101-3p ; hsa-mir-32-5p ; hsa-mir-22-3p ; hsa-mir-21-5p ; hsa-mir-16-5p ; hsa-mir-3190-3p ; hsa-mir-4698 ; hsa-mir-302c-5p ; hsa-mir-543 ; hsa-mir-374a-5p ; hsa-mir-5003-3p ; hsa-mir-127-5p ; hsa-mir-3143 ; hsa-mir-107 ; hsa-mir-103a-3p ; hsa-mir-3908 ; hsa-mir-8054 ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-4291 ; hsa-mir-3185 ; hsa-mir-761 ; hsa-mir-3619-5p ; hsa-mir-214-3p ; hsa-mir-922 ; hsa-mir-3617-3p ; hsa-mir-646 ; hsa-mir-34a-3p ; hsa-mir-1252-3p ; hsa-mir-3646 ; hsa-mir-551b-5p ; hsa-mir-5582-3p ; hsa-mir-665 ; hsa-mir-6079 ; hsa-mir-671-5p ; hsa-mir-6828-5p ; hsa-mir-7160-5p ; hsa-mir-6134 ; hsa-mir-7854-3p ; hsa-mir-7162-3p ; hsa-mir-4786-3p ; hsa-mir-484 ; hsa-mir-3155b ; hsa-mir-3155a ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-30d-5p ; hsa-mir-30e-5p ; hsa-mir-30c-5p ; hsa-mir-30b-5p ; hsa-mir-30a-5p
Nearest miRNA
hsa-mir-210/Upstream/4085019; hsa-let-7a-2/Downstream/10761;
Nearest TSS
ENST00000527297/Upstream/31434; ENST00000532965/Downstream/2560;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/31399, chr11-CpG: 51/Downstream/2107
Upstream sequence
gcctggccAGAAAGCAGATTTTTAAATTTGAGGTAAAGAAAGCTTAAACTTAAAAAGTTAATCAAATGCAATGGAAGCAAATAGACCTTCACCATTCTGA
Downstream sequence
TTTCCCATCACCAGAATGACCGATACATGGGGACTGTTGGTTCATCAATTATTTTGATTTATAAAGTTATAATATATAAGCCATATAAAAATTTCCAGTG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate