Basic Information
VIS ID
TVIS44029257
Fusion event
HTLV-1-SFSWAP integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr12
Cytoband
q24.33
Reference genome
NCBI36/hg18
Start
130783792/131733294 (Hg38)
End
130783792/131733294 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
SFSWAP
miRNAs that regulate target gene
hsa-mir-183-5p ; hsa-let-7a-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-let-7i/Upstream/3439116; hsa-mir-6763/Downstream/848703;
Nearest TSS
ENST00000382841/Upstream/6305; ENST00000537164/Downstream/19829;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/21385, chr12-CpG: 18/Downstream/1488
Upstream sequence
CGCGGTCTCCCTGGTACTTACTGGGCAGGTGCGTATCGTCAGGAGCTCCTCACCCTGCCCTGTGAGAACTTTCGTATGTGTGTCTCTGCCATCTCCTCCT
Downstream sequence
CCTCCCATTCCTGACCTGTTGAGCCAGGGGTGGATTGGCAGGCCTATAAGGCGCCTTTCACATTGAGGGTCTTAGGATTTGCAGTCCAGCTTTGCAGGGA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate