Basic Information
VIS ID
TVIS44029275
Fusion event
HTLV-1-RHBDF2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr17
Cytoband
q25.1
Reference genome
NCBI36/hg18
Start
72007879/76500202 (Hg38)
End
72007879/76500202 (Hg38)
Orient
-
Location type
Intronic
Target gene
RHBDF2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-7-5p ; hsa-mir-98-5p ; hsa-mir-615-3p ; hsa-let-7a-5p ; hsa-let-7b-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-2467-3p ; hsa-mir-3125 ; hsa-mir-3150b-3p ; hsa-mir-3179 ; hsa-mir-3202 ; hsa-mir-3622b-5p ; hsa-mir-3916 ; hsa-mir-4253 ; hsa-mir-4257 ; hsa-mir-4266 ; hsa-mir-4436b-3p ; hsa-mir-4458 ; hsa-mir-4476 ; hsa-mir-4500 ; hsa-mir-4632-5p ; hsa-mir-4688 ; hsa-mir-4695-5p ; hsa-mir-4779 ; hsa-mir-4784 ; hsa-mir-583 ; hsa-mir-6735-5p ; hsa-mir-6743-5p ; hsa-mir-6859-5p ; hsa-mir-6862-5p ; hsa-mir-6876-5p ; hsa-mir-6879-5p ; hsa-mir-765 ; hsa-mir-7843-5p
Nearest miRNA
hsa-mir-10226/Upstream/402126; hsa-mir-1250/Downstream/236248;
Nearest TSS
ENST00000595228/Upstream/7000; ENST00000590555/Downstream/1169;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/28128, chr17-CpG: 60/Downstream/708
Upstream sequence
CCCCAGTGAGGGAGCATCATTGAGAAGGAACCTGATGGACCAGCTGCTGCGcagggtttctcagcctcagcacagcccaacaccttgggctggataattc
Downstream sequence
ctcgttatgtgggctgttccgtgccctgaagatgtctggtagcgtccctggcctctacccactacctgccagtaacaacaacactcacttcccctcccaa
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate