Basic Information
VIS ID
TVIS44029278
Fusion event
HTLV-1-ABCA5 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr17
Cytoband
q24.3
Reference genome
NCBI36/hg18
Start
64779990/69272254 (Hg38)
End
64779990/69272254 (Hg38)
Orient
+
Location type
Intronic
Target gene
ABCA5
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-10226/Upstream/172598; hsa-mir-1250/Downstream/5476359;
Nearest TSS
ENST00000595228/Upstream/3380; ENST00000588110/Downstream/14007;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/670817, chr17-CpG: 116/Downstream/54314
Upstream sequence
TACTTTACTCCCAACCTAGTACCTTAACTGATCTCTTATCTCTAACTTGCAAGACCAGCTATGTACCCTGAGAAGAGAGACACATTATAAGTGAAGGAAC
Downstream sequence
CACAGCACAAGAGATACAAAAAGCTCTGCAAGGTGGGTAAGATACCACCCAATATATATACACACAGAGGCCAGTGGTTCAAAAAAAAGTGGTTTTATTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate