Basic Information
VIS ID
TVIS44029284
Fusion event
HTLV-1-ESRRB integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr14
Cytoband
q24.3
Reference genome
NCBI36/hg18
Start
76026545/76490449 (Hg38)
End
76026545/76490449 (Hg38)
Orient
-
Location type
Intronic
Target gene
ESRRB
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-19b-3p ; hsa-mir-6748-5p ; hsa-mir-6769b-5p ; hsa-mir-6769a-5p ; hsa-mir-5008-5p ; hsa-mir-4695-5p ; hsa-mir-552-3p ; hsa-mir-6768-5p
Nearest miRNA
hsa-mir-208a/Upstream/2010245; hsa-mir-1185-1/Downstream/775769;
Nearest TSS
ENST00000550708/Upstream/50807; ENST00000611036/Downstream/9197;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/50735, chr14-CpG: 16/Downstream/1073
Nearest cancer related gene
ESRRB(TSG, No orient, 0)
Upstream sequence
TTTGCCTAATTTAAGTGCATGTATAATGCAATTCCAGTACATTATCATTGTTCTGCAGTGAGAACTTTCATCTCATCATTAGTAATAATAGCTCAGTAAA
Downstream sequence
TACTTTGTATATTCTGGAATCATCGTctcatttagacctcacagcaactctctgaagtagaccctactattatactatttcctagatgaggaagctaagg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate