Basic Information
VIS ID
TVIS44029296
Fusion event
HTLV-1-SORCS3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
q25.1
Reference genome
NCBI36/hg18
Start
106958748/105209000 (Hg38)
End
106958748/105209000 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
SORCS3
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-26b-5p
Nearest miRNA
hsa-mir-107/Upstream/940595; hsa-mir-202/Downstream/5689090;
Nearest TSS
ENST00000439456/Upstream/50072; ENST00000424701/Downstream/610197;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/565946, chr10-CpG: 100/Downstream/1955022
Upstream sequence
TACTTGGCAGCAGTGTCTGTTTCTCCTTCCTTCCTTCCAGCTTCATTTAAACATGCCAATATAAGACTGATCTCAAGTTCCACCTTTCTATGTAGAAATC
Downstream sequence
CATGATTCTTGTCACATTAACTCCACAGGAATCTGTTGGGCACTTGGGGCTACTCTCTGCAGTCCACATTGTAGCATCAGTTATGGGCCCACAGTCTTCC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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