Basic Information
VIS ID
TVIS44029299
Fusion event
HTLV-1-AKAP9 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
q21.2
Reference genome
NCBI36/hg18
Start
91546198/92078948 (Hg38)
End
91546198/92078948 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7E
Target gene
AKAP9
miRNAs that regulate target gene
hsa-mir-192-5p ; hsa-mir-21-5p
Nearest miRNA
hsa-mir-10525/Upstream/16163679; hsa-mir-10399/Downstream/125067;
Nearest TSS
ENST00000635602/Upstream/8810; ENST00000435423/Downstream/4628;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/137914, chr7-CpG: 115/Downstream/54833
Nearest cancer related gene
AKAP9(OG, No orient, 0)
Upstream sequence
ATCAGCAACTAAAAGCTTATATTACTTTATACTTAACAGAACTTTCTGAGCCTTGTTTGATATGATGGGGGAGATATTGGTCTATAATGAAATTAAGTAG
Downstream sequence
TATGTCTGAGAAGTAGTGTATTATTTTTGTGTGTGATCATCTCTTTGAGGTACTGCCCTAAAATAAAGTAAAATTTTCAAAATGTAAATACATATATATT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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