Basic Information
VIS ID
TVIS44029350
Fusion event
HTLV-1-ALCAM integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
q13.11
Reference genome
NCBI36/hg18
Start
106641476/105439942 (Hg38)
End
106641476/105439942 (Hg38)
Orient
-
Location type
Intronic
Target gene
ALCAM
miRNAs that regulate target gene
hsa-mir-192-5p ; hsa-mir-215-5p ; hsa-mir-148b-3p ; hsa-mir-483-5p ; hsa-mir-323a-5p ; hsa-mir-148a-3p ; hsa-mir-152-3p ; hsa-mir-9-5p
Nearest miRNA
hsa-let-7g/Upstream/1915826; hsa-mir-12124/Downstream/4162886;
Nearest TSS
ENST00000440867/Upstream/604; ENST00000460954/Downstream/73383;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/70447, chr3-CpG: 84/Downstream/428493
Upstream sequence
AAAATCCCTGTGATGCAGACACTGTTCTATttgttgttgtcattgttgttactgttgttgATATTTGGCTATAACATAAGAGGAAAAGTGTGCTTATAGA
Downstream sequence
GATATTTTCTTTTCTATTCTGTGAATATCATAAAAAGTAAGGTTAGTAAATGTTATAAATGAATTCTGTCAGAAAACACTTTATAAAAGGAAAAATCTCA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate