Basic Information
VIS ID
TVIS44029351
Fusion event
HTLV-1-ADRA1B integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
q33.3
Reference genome
NCBI36/hg18
Start
159323744/159964159 (Hg38)
End
159323744/159964159 (Hg38)
Orient
+
Location type
Intronic
Target gene
ADRA1B
miRNAs that regulate target gene
hsa-mir-10b-5p
Nearest miRNA
hsa-mir-10397/Upstream/5134619; hsa-mir-103a-1/Downstream/510243;
Nearest TSS
ENST00000502646/Upstream/26393; ENST00000520274/Downstream/44954;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/47294, chr5-CpG: 95/Downstream/7838
Upstream sequence
GAGAAATTCACTATGGATTTGGGTGGTGTGCAAGATTGAAATGACATCTAGAGATAGCACAAGAAACCGTGAGTCACATATTCAGTCAGTCCAtcactga
Downstream sequence
gcaaatatctatttcagcacctactacgtgtgccagggcctgggctCTCCagagacaaagtggttccctgttcacttctctttcaatcctttaggttcct
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate