Basic Information
VIS ID
TVIS44029355
Fusion event
HTLV-1-MRPS9 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
q12.1
Reference genome
NCBI36/hg18
Start
105077591/105094701 (Hg38)
End
105077591/105094701 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
MRPS9
miRNAs that regulate target gene
hsa-mir-193b-3p
Nearest miRNA
hsa-mir-1285-2/Upstream/2662335; hsa-mir-10b/Downstream/4046789;
Nearest TSS
ENST00000437798/Upstream/2603; ENST00000452037/Downstream/3936;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/56388, chr2-CpG: 85/Downstream/49155
Upstream sequence
TAGGAAATGTGTGTTTATTTTATTTGTGTGTGCCTGTGTCAACAAGCAGTGCATTCTTAACTCCATTTAAGATGAATTAGTTCTGCTATTATCCTCACAG
Downstream sequence
GACAGGGGATGGAAGAAGCTTTTATTTCCCTTAGGAAAAGCCAGAGAGAAACCCATACCCCAGGGTTTGATAACTTCAACATTGGGAACTATAGGAGGAC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate