Basic Information
VIS ID
TVIS44029370
Fusion event
HTLV-1-PLCB2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr15
Cytoband
q15.1
Reference genome
NCBI36/hg18
Start
38373482/40293989 (Hg38)
End
38373482/40293989 (Hg38)
Orient
-
Location type
Intronic
Target gene
PLCB2
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-4762-5p
Nearest miRNA
hsa-mir-1233-1/Upstream/3321088; hsa-mir-10393/Downstream/1397596;
Nearest TSS
ENST00000557528/Upstream/367; ENST00000559520/Downstream/3730;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/2401, chr15-CpG: 160/Downstream/28909
Upstream sequence
ACAGCTAAGCTCTGAGGACCAGGGTGCTTCTAGCATGAAGGGAAGAGGTGGGCCTCCCACCTCCCTCCCTAGCCAAAGAGGGAACAATGCCTTCCCCCAG
Downstream sequence
GACCTGGGGCTCCGGCTGCCCCACTCTGCCCACTCTTCCTCCCCTCCCCCACCCCAGCCTCAGCCCTTCCCGTTGGTTTCCATGGGGACCAAGTGGCAGC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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