Basic Information
VIS ID
TVIS44029380
Fusion event
HTLV-1-TSPAN11 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr12
Cytoband
p11.21
Reference genome
NCBI36/hg18
Start
30997932/30953731 (Hg38)
End
30997932/30953731 (Hg38)
Orient
+
Location type
Intronic
Target gene
TSPAN11
miRNAs that regulate target gene
hsa-mir-629-3p ; hsa-mir-6867-3p ; hsa-mir-4713-5p ; hsa-mir-6799-5p ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-4726-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6840-3p ; hsa-mir-7113-5p ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-6876-5p ; hsa-mir-4476
Nearest miRNA
hsa-mir-1244-3/Upstream/5079652; hsa-let-7i/Downstream/11369969;
Nearest TSS
ENST00000382841/Upstream/26773; ENST00000535317/Downstream/107019;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/26787, chr12-CpG: 67/Downstream/119678
Upstream sequence
CGTGTAGGACAGGTAAACTTGTGTCCTGCAACCCTGGTGAGACAGGAAAAGAGATTAAGAACACAGTAAGACCAGCGCAAATTCTGTGGGAGACTTGTAG
Downstream sequence
GTTAGACCTTTGTCAAGAGGACAAAACTGACATCTAAAGGTCTGGAAGATTCTGCCCCAATTCACCTCTATTTGGTCTCCTTAGCAATTCCCACATCTTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate