Basic Information
VIS ID
TVIS44029384
Fusion event
HTLV-1-DPYD integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p21.3
Reference genome
NCBI36/hg18
Start
98143908/97905764 (Hg38)
End
98143908/97905764 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1M
Target gene
DPYD
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-302b-3p ; hsa-mir-494-5p
Nearest miRNA
hsa-mir-101-1/Upstream/3361985; hsa-mir-11399/Downstream/139478;
Nearest TSS
ENST00000473358/Upstream/108799; ENST00000418344/Downstream/15233;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/1183501, chr1-CpG: 47/Downstream/14869
Upstream sequence
TGTGGATTAGACGCCATTCATACCTTGCTTCATTTACACATGTGAAGGACTCCTTGAAGAACCGAATATTAAACATCTTATTGAGAAACTCAGTGAATAC
Downstream sequence
ATACGGTCAGGAAAAATGAGGTAACTTTTGAAGGACTTCCCACTTCTATACCTCTATGATTCCTAATTTTCATGTCATGTATTTTAATGTCTGAATAAAC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate