Basic Information
VIS ID
TVIS44029385
Fusion event
HTLV-1-TSPAN2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p13.2
Reference genome
NCBI36/hg18
Start
115409403/115065259 (Hg38)
End
115409403/115065259 (Hg38)
Orient
+
Location type
Intronic
Target gene
TSPAN2
miRNAs that regulate target gene
hsa-mir-1277-5p ; hsa-mir-297 ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-511-3p ; hsa-mir-5011-5p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-4742-3p ; hsa-mir-452-3p ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-let-7f-2-3p ; hsa-mir-1284 ; hsa-mir-664a-3p ; hsa-mir-6074 ; hsa-mir-5683 ; hsa-mir-4282
Nearest miRNA
hsa-mir-101-1/Upstream/2183130; hsa-mir-1182/Downstream/1494765;
Nearest TSS
ENST00000473358/Upstream/6834; ENST00000448680/Downstream/24155;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/209938, chr1-CpG: 72/Downstream/23970
Upstream sequence
GCTGAAGGGAAAAGCAGAAGAAATTCTACAAGAGGAAAGGTTCCCTGGGCGTGCCGGATCCAGTTCCAAATCTGGCTCTAATACTCCGCATGCCATAAGG
Downstream sequence
CCACCTGTGGCTTCCAAGGATACTTTATCCTTCTTATGGTCTGACCCTCAAAAAATAGCTGCTGAATGTAATAATTAATTTACAGCCACATTTTAAATTC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate