Basic Information
VIS ID
TVIS44029387
Fusion event
HTLV-1-CZIB integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p32.3
Reference genome
NCBI36/hg18
Start
53458314/53220054 (Hg38)
End
53458314/53220054 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1B
Target gene
CZIB
miRNAs that regulate target gene
hsa-mir-30e-5p ; hsa-mir-376a-5p ; hsa-mir-376a-3p ; hsa-mir-205-5p ; hsa-mir-485-5p
Nearest miRNA
hsa-mir-12136/Upstream/1383652; hsa-mir-101-1/Downstream/834025;
Nearest TSS
ENST00000473358/Upstream/134; ENST00000569869/Downstream/522;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/22911, chr1-CpG: 44/Downstream/170
Upstream sequence
AGGCGAACTATTCACCTTATTAAATAATCACAAGCGTCCCTTCAAGTAGCATTTCGTTTAGTGTCCATTTACAGACCACGAAATATTTAACACAGGGAAG
Downstream sequence
AACTACAAAATGAAGCTTTCCAAGACTGCCAATTAGAGATAAACCAATACACTTTAATAGAAAGCAAACGTAAAATTCTAACTAGGAAAACCCCGAACAC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate