Basic Information
VIS ID
TVIS44029394
Fusion event
HTLV-1-ADAMTS12 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
p13.3
Reference genome
NCBI36/hg18
Start
33567895/33532033 (Hg38)
End
33567895/33532033 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA5A
Target gene
ADAMTS12
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-26b-5p
Nearest miRNA
hsa-mir-10397/Upstream/1137558; hsa-mir-103a-1/Downstream/2615859;
Nearest TSS
ENST00000502646/Upstream/9803; ENST00000330120/Downstream/92318;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/29775, chr5-CpG: 25/Downstream/360053
Upstream sequence
CATTTAGATGATGACCGTGAGCCCAACATGATGACAGGGCTCAATTACATCAGTTCTCCCTATTGCTGTGAAACAATGAAGGCTTGTTGTGTTCATTAGT
Downstream sequence
CAATTGGATTCCACTTCCAAAGTACATACAATGCTTATAATTATGGGCAACTTGGAGGGGAGATCCCAATTTGCCTCTGCTGGTTCAACAAAAATCACAT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate