Basic Information
VIS ID
TVIS44029409
Fusion event
HTLV-1-RBM47 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
p14
Reference genome
NCBI36/hg18
Start
40326367/40629593 (Hg38)
End
40326367/40629593 (Hg38)
Orient
-
Location type
Intronic
Target gene
RBM47
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-124-3p ; hsa-mir-335-5p ; hsa-mir-3658 ; hsa-mir-516b-5p ; hsa-mir-3191-5p ; hsa-mir-3653-3p ; hsa-mir-504-3p ; hsa-mir-298 ; hsa-mir-4670-3p ; hsa-mir-6824-3p ; hsa-mir-6764-3p ; hsa-mir-330-5p ; hsa-mir-326 ; hsa-mir-518c-5p ; hsa-mir-216b-5p ; hsa-mir-122-5p ; hsa-mir-627-3p ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-mir-382-3p ; hsa-mir-129-5p ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-4778-3p ; hsa-mir-877-3p
Nearest miRNA
hsa-mir-12113/Upstream/127474; hsa-mir-1243/Downstream/7023076;
Nearest TSS
ENST00000502981/Upstream/64; ENST00000473399/Downstream/271;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/190705, chr4-CpG: 66/Downstream/130
Upstream sequence
TTCTCGTCCGCCTTCTTTTTAATGTAAAACCAAAATAAGGAGTGTCCAGCGACTCCCCACCGCGCCGCTTAAAGCAACAGAGCGTTTTAGGCTTAACTCC
Downstream sequence
CAGGCTCTGGGAATTCCAGTGGGTCAGAATTGCTTAACCTTGGAGACTTGCAGAGAGAAAGTCTCCAGGAGGACCGCTCCCCAAACCCTGGTTTCTCTCT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate