Basic Information
VIS ID
TVIS44029421
Fusion event
HTLV-1-ARHGEF28 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
q13.2
Reference genome
NCBI36/hg18
Start
72965091/73633510 (Hg38)
End
72965091/73633510 (Hg38)
Orient
+
Location type
Intronic
Target gene
ARHGEF28
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-19b-3p ; hsa-mir-203a-3p ; hsa-mir-4635 ; hsa-mir-302a-5p ; hsa-mir-7161-3p ; hsa-mir-338-3p ; hsa-mir-7157-5p ; hsa-mir-4310 ; hsa-mir-1226-3p ; hsa-mir-634 ; hsa-mir-6771-3p
Nearest miRNA
hsa-mir-10397/Upstream/754847; hsa-mir-103a-1/Downstream/9206645;
Nearest TSS
ENST00000502646/Upstream/7314; ENST00000510131/Downstream/51322;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/6808, chr5-CpG: 29/Downstream/275975
Upstream sequence
tgctgcttctagcttgtcttggccaagtcacctaaacttttagcctcagtttttgtctatttctctcataagattgtaaaaaggactcaataagatagtc
Downstream sequence
tatataaagtgtttagcacagaacctaagagaataactcctcaataaacaatacctttaAttttttttttttttttttttttttgagacagagtctcgtt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate