Basic Information
VIS ID
TVIS44029424
Fusion event
HTLV-1-RNF144A integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
p25.1
Reference genome
NCBI36/hg18
Start
7022822/6965240 (Hg38)
End
7022822/6965240 (Hg38)
Orient
+
Location type
Intronic
Target gene
RNF144A
miRNAs that regulate target gene
hsa-mir-125b-5p ; hsa-mir-335-5p ; hsa-mir-26b-5p ; hsa-mir-24-3p
Nearest miRNA
hsa-mir-7158/Upstream/314801; hsa-mir-10b/Downstream/3227374;
Nearest TSS
ENST00000437798/Upstream/32156; ENST00000433456/Downstream/13384;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/46938, chr2-CpG: 19/Downstream/66925
Nearest cancer related gene
RNF144A(TSG, No orient, 0)
Upstream sequence
TTGCTCCACCATAGCTGGCAGGCCTGTTGTGAGGATATTTACAAGAAATGTGAAACAACCTTGCAGACACATGCACTGGGACGAGGCAAGGCTTTTCTGG
Downstream sequence
GCCTGGAGGGAAAATAGGGAAATAGGACACGATCTCAGCTCATGAGGAGGGTGTGTCGGAGGCTGTCATAGGAGGCAGTGGTGCCCTGCAAGGTGGGGAG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate