Basic Information
VIS ID
TVIS44029440
Fusion event
HTLV-1-PPP2R5A integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
q32.3
Reference genome
NCBI36/hg18
Start
210587052/212347087 (Hg38)
End
210587052/212347087 (Hg38)
Orient
+
Location type
Intronic
Target gene
PPP2R5A
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-590-3p ; hsa-mir-335-5p ; hsa-mir-484
Nearest miRNA
hsa-mir-101-1/Upstream/269402; hsa-mir-1182/Downstream/7770766;
Nearest TSS
ENST00000473358/Upstream/15374; ENST00000472389/Downstream/30619;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/60735, chr1-CpG: 77/Downstream/67162
Upstream sequence
TGGGTCTTTTTCTCTTGGATTTCCCTATAATTAGAGGTTTCTTATTTTAAAAAGTATTTCTTTGAGGAAACTTATCTTTCTTATTAATTATTAAGTTGAA
Downstream sequence
TATTCCAGGTGAAATGACAATCTGTTATCTTCACATATGGCGAGTTTTGGCAAAGGCATATGTAGTTCAGTAGGAAACATCTTCTTTTTTAAGATTGATA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate