Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene139639620138946720139293557139273752139331671139274102139283477139270932139279161139292919139296765139261941139263850139245960139247027139251454139252191139287671139288195139268601139268800139284670139284852139281172139281341139282332139282481139288292139288441139293170
Basic Information
VIS ID
TVIS44029460
Fusion event
HTLV-1-MATR3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
q31.2
Reference genome
NCBI36/hg18
Start
138656758/139293170 (Hg38)
End
138656758/139293170 (Hg38)
Orient
+
Location type
Intronic
Target gene
MATR3
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-200b-3p ; hsa-mir-1-3p ; hsa-mir-7-5p ; hsa-mir-26b-5p ; hsa-mir-24-3p ; hsa-mir-744-5p ; hsa-mir-615-3p ; hsa-mir-186-5p ; hsa-mir-185-5p ; hsa-mir-149-5p ; hsa-mir-125b-5p ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-mir-18a-5p ; hsa-let-7e-5p ; hsa-mir-16-1-3p ; hsa-mir-302c-5p ; hsa-mir-3143 ; hsa-mir-4659a-3p ; hsa-mir-4659b-3p ; hsa-mir-6875-3p ; hsa-mir-3942-3p ; hsa-mir-5100 ; hsa-mir-2276-3p ; hsa-mir-4708-3p ; hsa-mir-4772-3p ; hsa-mir-4330 ; hsa-mir-10b-3p ; hsa-mir-1245b-3p ; hsa-mir-4802-3p ; hsa-mir-33a-3p ; hsa-mir-613 ; hsa-mir-206 ; hsa-mir-338-5p ; hsa-mir-5094 ; hsa-mir-543
Nearest miRNA
hsa-mir-10397/Upstream/1645521; hsa-mir-103a-1/Downstream/1270501;
Nearest TSS
ENST00000502646/Upstream/17061; ENST00000504023/Downstream/364;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/19008, chr5-CpG: 112/Downstream/303
Upstream sequence
acgagacaccatctctacggaaaaaataaaaataaaaaagttagctggccatggtggtgcgagcctgtagtcccagctactggggaggctgaggtgggag
Downstream sequence
gatcccttgaggataggagttcgaggctgcaatgagccatgataacgccagcgcactccaacctgagcaacacagTTTATTTATGATAAATAAATAAACA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate