Basic Information
VIS ID
TVIS44029463
Fusion event
HTLV-1-CPEB3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
q23.32
Reference genome
NCBI36/hg18
Start
93977792/92228055 (Hg38)
End
93977792/92228055 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
CPEB3
miRNAs that regulate target gene
hsa-mir-26a-5p ; hsa-mir-29a-3p ; hsa-mir-23b-3p ; hsa-mir-196a-5p ; hsa-mir-21-5p ; hsa-mir-320a ; hsa-let-7b-5p ; hsa-mir-8485 ; hsa-mir-513a-3p ; hsa-mir-513c-3p ; hsa-mir-3606-3p ; hsa-mir-205-5p ; hsa-mir-3978 ; hsa-mir-6124 ; hsa-mir-3148 ; hsa-mir-922 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-3714 ; hsa-mir-548an ; hsa-mir-548e-5p ; hsa-mir-5047 ; hsa-mir-1301-3p ; hsa-mir-7156-3p ; hsa-mir-103a-3p ; hsa-mir-107 ; hsa-mir-25-3p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-32-5p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-377-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-342-3p ; hsa-mir-4328 ; hsa-mir-548au-3p ; hsa-mir-449b-5p ; hsa-mir-449a ; hsa-mir-34c-5p ; hsa-mir-34a-5p
Nearest miRNA
hsa-mir-107/Upstream/2635228; hsa-mir-1287/Downstream/3836260;
Nearest TSS
ENST00000439456/Upstream/247535; ENST00000462465/Downstream/15191;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/181967, chr10-CpG: 84/Downstream/11319
Upstream sequence
tagctcactgcaacctccacctcccggattcaagctattctcctgccttagcctctgagtagctgggactacagacgtgcaccaccacacctggctaatt
Downstream sequence
ttttgtatttttagtagagacaggctctcaccatgtttgccagcctggtctcaaactcctgacctcaggtgatctgcccatcttggcctcccaaagtgct
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate