Basic Information
VIS ID
TVIS44029470
Fusion event
HTLV-1-KDSR integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr18
Cytoband
q21.33
Reference genome
NCBI36/hg18
Start
59184467/63366254 (Hg38)
End
59184467/63366254 (Hg38)
Orient
-
Location type
Intronic
Target gene
KDSR
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-124-3p ; hsa-mir-16-5p ; hsa-mir-423-3p ; hsa-mir-92a-3p ; hsa-mir-607 ; hsa-mir-4698 ; hsa-mir-8063 ; hsa-mir-205-3p ; hsa-mir-34a-3p ; hsa-mir-498 ; hsa-mir-6869-5p ; hsa-mir-4279 ; hsa-mir-1200 ; hsa-mir-566 ; hsa-mir-6789-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-544b ; hsa-mir-4324 ; hsa-mir-5089-5p ; hsa-mir-6807-5p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-892b ; hsa-mir-193b-3p ; hsa-mir-193a-3p ; hsa-mir-1343-3p ; hsa-mir-23a-5p ; hsa-mir-23b-5p ; hsa-mir-660-3p ; hsa-mir-6742-3p ; hsa-mir-6778-3p ; hsa-mir-6783-3p ; hsa-mir-6791-3p ; hsa-mir-6829-3p ; hsa-mir-6836-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-106b-3p ; hsa-mir-129-5p ; hsa-mir-3672 ; hsa-mir-4524a-3p ; hsa-mir-4797-5p ; hsa-mir-5007-5p ; hsa-mir-6760-3p ; hsa-mir-6814-3p ; hsa-mir-6864-3p ; hsa-mir-6872-5p ; hsa-mir-8055
Nearest miRNA
hsa-mir-1-2/Upstream/4915096; hsa-mir-5011/Downstream/3715330;
Nearest TSS
ENST00000575820/Upstream/10740; ENST00000589905/Downstream/874;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/45201, chr18-CpG: 124/Downstream/227
Upstream sequence
AGGCAAGGAGGCATTCTCTCTGTTTAAGAAAGGTGCCACATTTGCAGAACAGGGATCGCTGAATATGCGAGCTTCCGCCAAGAAATAAATCACACCTATC
Downstream sequence
CACCTCTCCTTCATTCCTCGCACACAAGCCTTGTCGTTTAGCTCATCCTTCCCACTAGAAAACAGCAAAGGATTGCATTGGAGCAGCAATCAGCAGATGC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate