Basic Information
VIS ID
TVIS44029476
Fusion event
HTLV-1-MICAL2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr11
Cytoband
p15.3
Reference genome
NCBI36/hg18
Start
12095656/12117533 (Hg38)
End
12095656/12117533 (Hg38)
Orient
-
Location type
Intronic
Target gene
MICAL2
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-6786-3p ; hsa-mir-4324 ; hsa-mir-4329 ; hsa-mir-5000-3p ; hsa-mir-4436a ; hsa-mir-4293 ; hsa-mir-4740-5p ; hsa-mir-7153-5p ; hsa-mir-146b-5p ; hsa-mir-146a-5p ; hsa-mir-589-5p ; hsa-mir-6857-3p ; hsa-mir-4251 ; hsa-mir-5188 ; hsa-mir-4773 ; hsa-mir-4730 ; hsa-mir-6850-5p ; hsa-mir-675-5p ; hsa-mir-4466 ; hsa-mir-4664-5p ; hsa-mir-342-5p ; hsa-mir-25-5p ; hsa-mir-5580-5p ; hsa-mir-3692-5p ; hsa-mir-5739 ; hsa-mir-185-5p ; hsa-mir-1908-5p ; hsa-mir-1911-3p ; hsa-mir-197-5p ; hsa-mir-3132 ; hsa-mir-3150b-3p ; hsa-mir-3170 ; hsa-mir-3529-5p ; hsa-mir-3614-5p ; hsa-mir-379-5p ; hsa-mir-4253 ; hsa-mir-4306 ; hsa-mir-4325 ; hsa-mir-4644 ; hsa-mir-4784 ; hsa-mir-5090 ; hsa-mir-5572 ; hsa-mir-6087 ; hsa-mir-6502-3p ; hsa-mir-663a ; hsa-mir-6731-5p ; hsa-mir-6737-5p ; hsa-mir-6758-5p ; hsa-mir-6760-5p ; hsa-mir-6775-5p ; hsa-mir-6787-5p ; hsa-mir-6812-5p ; hsa-mir-6819-5p ; hsa-mir-6855-5p ; hsa-mir-6856-5p ; hsa-mir-6862-5p ; hsa-mir-6881-5p ; hsa-mir-744-5p ; hsa-mir-8085
Nearest miRNA
hsa-mir-210/Upstream/334311; hsa-let-7a-2/Downstream/46150;
Nearest TSS
ENST00000527297/Upstream/837; ENST00000532420/Downstream/3942;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/6064, chr11-CpG: 72/Downstream/260077
Upstream sequence
GCAGAAACTACTTCTTTGTTCCCACGACTCTGAATGGCTGGCCCTGGCCACTTATCTGAATACTGACTTATCTGGTGAAGCTTTGCAGGATCTCAGTATA
Downstream sequence
TAGTGTGTTGGAGCCAGGATAATGAGGTGTAGGGGAGACTGAAGAAGCAGCTCTCACTAACAAGAGCTGCCCTCTGAAACAGAGTGGGCCCAGGGTCTGC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate